Sociodemographic determinants of low birthweight in Greece: A population study

A total population sample of 10,654 singleton births from the Greek National Perinatal Survey of April 1983 was analysed to identify factors independently associated with low birthweight (LBW). The sample was divided into two groups according to the gravidity of the mothers (3368 primigravidae and 7286 multigravidae). Data examined included regional characteristics, marital status, age at and duration of marriage, parental ages at delivery, crowding in the home, insurance status, parental occupational classification and parental education levels. Logistic regression was used to define the socioeconomic and demographic characteristics independently associated with the delivery of an LBW singleton baby. Significantly different LBW rates were found among the two groups: 4.3% in the primigravidae and 5.2% for multigravidae. For primigravidae significant associations were found with marital status, maternal occupation and father's education, while for multigravidae significant features were mother's education and place (region) of residence. The study showed little to assist in devising strategies of primary prevention of LBW in Greece. This study examines the sociodemographic determinants of low birth weight (LBW) in Greece. The study population comprised 10,654 singleton births (3368 primigravid and 7286 multigravid mothers) from the Greek National Perinatal Survey of April 1983 was used to identify factors associated with LBW. The study considered classifications based on parental occupations, educational levels, marital status and parental ages, with the ultimate aim of providing clues about causal etiology. The results indicated no significant correlation with paternal occupation group. There was, however, a significant association with maternal occupation group. The housewife, whether primigravid or multigravid, had the lowest risk of having an LBW baby as compared to laborers and commercial workers. In Greece, paternal and maternal education showed a significant relationship with LBW. Unmarried primigravidas had a significant residual risk of LBW; however, marital status was not an independent risk factor for multigravidas. The mother's age was significantly associated with LBW among multigravidas, the highest rate being found among the oldest group of mothers. Paternal age was also significantly related to LBW among multigravidas, with women whose husband was either a teenager or age 45 or older being most at risk. In conclusion, factors such as maternal age and social class based on the father's occupation are not independently associated with LBW in Greece. For primigravidas significant associations were found with marital status, maternal occupation and father's education, while for multigravidas significant features were the education and place of residence of the mother

Colloid clearance rate changes in children with homozygous-β-thalassemia in relation to blood transfusion

The plasma clearance rate of heat denatured human serum albumin (DHAI-125, 5 mg/kg body weight) was studied in 20 children with homozygous-β-thalassemia before and 7-10 days after blood transfusion. A significant increase of the DHAI-125 clearance rate (P<0.02) was found 7-10 days after blood transfusion while the spleen presented its minimum size. This finding may be relevant to the improved intrasplenic blood circulation after blood transfusion due to the release of the blood trapped within the spleen. © 1980 Springer-Verlag